Bhadange Shital Shankar*, Nainav Krushna Kailas*, Borase Yogini Dilip*, Ghongade Rupali Prakash*, Patil Dnyaneshwar Rajendra Patil*, Prof. P. S. Patil (M Pharm) and Dr. M. R. Bhurat (M Pharm, PhD)


To formulate and evaluate herbal cream using Aloe Vera gel, dimethyl sulphoxide extracts of Neem (Azadirachta indica) and Tulsi (Ocimumtenuiflorum) to give multipurpose effect. The cream was prepared by using the cream base that is bee’s wax, liquid paraffin, borax, methylparaben, distilled water, rose oil, Aloe Vera gel, dimethyl sulphoxide extracts of Neem and Tulsi. The cream was prepared by using the slab technique/extemporaneous method for geometric and homogenous mixing of all the excipients and the herbal extracts. By using slab technique, we have developed three batches of our herbal cream, namely F1, F2, F3, F4, All three batches were evaluated for different parameters like appearance, PH, viscosity, phase separation. All the three formulations F1, F2, F3, F4 showed good appearance, PH, adequate viscosity and no phase separation was observed. Also, the formulations F1, F2, F3, F4 showed no redness, erythema and irritation during irritancy study and they were easily washable. All the three All three herbal ingredients showed significant different activities. Based on the results, we can suggest that all the three formulations F1, F2, F3, F4, were stable and can be safely used on the skin.

Keywords: Aloe barbadensis (gel), Azadirachta indica (Neem), Ocimum tenuiflorum/Ocimum sanctum (Tulsi), Herbal cosmetic, Multipurpose crea.

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