Abstract
CASE REPORT KARTAGENER’S SYNDROME

Rohit Barsola* and Vishnu Kant

ABSTRACT

Background: Kartagener’s syndrome is a subset of primary ciliary dyskinesia, an autosomal recessive inherited disorder characterized by the clinical triad of chronic sinusitis, bronchiectasis, and situs inversus. Abnormal ciliary structure or function leading to impaired ciliary motility is the main pathophysiologic problem in Kartagener’s syndrome. Case Presentation: A 47 year old female presented with productive cough from one month and hemoptysis. She suffered from similar complaints 1 year back. Laboratory workup showed leukocytosis (>12000 cells) Clinical and imaging findings revealed chronic sinusitis, bronchiectasis, dextrocardia, and situs inversus and she was diagnosed with kartagener syndrome. She was given medical treatment in the form of antibiotics, antipyretics, mucolytics, inhaled bronchodilators and nebulizer solution. Conclusion: Patients with Kartagener’s syndrome present with chronic recurrent sinopulmonary infections. As the correct diagnosis is often delayed by years, it may cause chronic respiratory problems with reduced quality of life. Genetic counseling and fertility issues should be addressed once Kartagener’s syndrome is diagnosed.

Keywords: Kartagener’s syndrome, Primary ciliary dyskinesia, Chronic sinusitis, Bronchiectasis, Situs inversus.


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