Abstract
FORMULATION AND EVALUATION OF FAST DISINTEGRATING TABLETS OF NITROGLYCERIN BY USING FLAX SEED POWDER AS SUPERDISINTEGRANT

Rishabh Chaurasiya*, Pranav Kumar Upadhyay, Kakli Rai, Sushma Singh and Aditi Singh

ABSTRACT

The aim of the present research work were to formulate and evaluate the fast disintegrating tablets (sublingual) of Nitroglycerin by using the Flax seed mucilage extract powder. Now a days, the drug delivery system are becoming more difficult day by day, as pharmaceutical researchers dealing with new techniques for the better understanding of biochemical and physico-chemical properties to make their performance better. In the last 10 years, the fast disintegrating tablet (sublingual) demand has been increased, because of the pediatric patients and geriatric patients due to the problem of swallowing, and due to the properties of fast disintegrating for the effective emergency treatment. The superdisintegrant used in this study was flax seed mucilage extract powder and croscarmellose. The tablets of Nitroglycerin were evaluated for hardness, friability, disintegration time study.

Keywords: Fast disintegrating tablets, Nitroglycerin, Flax seed mucilage extract powder, Croscormellose, superdisintegrant.


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