European Journal of Biomedical and Pharmaceutical Sciences

ASSESSMENT OF ANTIMICROBIAL THERAPY AND ITS THERAPEUTIC OUTCOMES IN INFECTIOUS DISEASES WITH STEWARDSHIP PROGRAM

Lerin Aaron J. G.*, Evin Vincent, Mohammed Muzzamil, Dany Harshan P., R. Sivasakthi, J. Subadradevi, D. Saranya S. Priya and Dr. Ramasamy Sethuraman

ABSTRACT

Antibiotics may lead to drug resistance and serious adverse drug reactions. The resistance to many bacterial strains, Adverse Drug Reaction, reduced Pharmacological effect and increased side effects. Antimicrobial stewardship programs help to develop the systematic approach in treatment, avoid the Irrational use of antibiotics and improve patient treatment outcomes. Rational use of antibiotics may reduce the antibiotic Resistance, adverse drug reactions and other side effects. The monitoring of prescription pattern of antimicrobials by Antibiotic stewardship programme may improve the patient Outcomes. The present study assess the therapeutic outcomes in patient treated with various antimicrobial agents. Total of 250 study population were included in the study, and found that, 52% were female and 48% were male patients. Urinary tract infection is the most common clinical symptom in 42%. and mostly prescribed antibiotic was Cephalosporins 60% and Sulpha group of antibiotics were in 26%. The magnitude of symptoms decreased in 225 patients by Stewardship Programme. 78% patients received Rational use of drug and 22% were received Irrational use of drug as per CDC guidelines. The study conclude that, The Utilization of antibiotic should be carefully monitored and Periodically reviewed for better patient care. It is a process for effective patient care. The clinical pharmacist should carryout the Surveillance programme and frame the antimicrobials usage Policy.

Keywords: Rational use, Antimicrobials, Stewardship programs, Therapeutic outcome.