European Journal of Biomedical and Pharmaceutical Sciences

TREATMENT AND CLINICAL OUTCOME OF PATIENTS WITH CORONAVIRUS DISEASE

*Razia Ansari, R.Shivani and Dr. Nikhil Kumar Vanajari

ABSTRACT

The COVID-19 outbreak has brought our lives to a sudden and complete lockdown. While the numbers of confirmed cases and deaths still rise, people round the world are taking brave actions to mitigate transmission and save lives. Coronavirus disease 2019 (COVID-19) is an infectious disease caused by coronavirus-2 (SARS-CoV-2) that causes a severe acute respiratory syndrome, a characteristic hyper inflammatory response, vascular damage, micro-angiopathy, angiogenesis and widespread thrombosis. During this emergency period of the COVID-19 outbreak, clinical researchers are using and testing a spread of possible treatments. Combination treatment of low-dose systematic corticosteroids and anti-virals, anti- coagulants, use of statins, zinc , role of vitamin C, D and convalescent plasma have been encouraged as part of critical COVID-19 management. Vaccine-associated enhanced disease has been rarely encountered with existing vaccines or viral infection. Safe and effective vaccines are a game-changing tool: but for the foreseeable future we must continue wearing masks, cleaning our hands, ensuring good ventilation indoors, physically distancing and avoiding crowds. But it’s not vaccines that will stop the pandemic, it’s vaccination. We must all do our part to keep each other safe until this outbreak subsides and humanity are back to being greater than ever.

Keywords: COVID-19, Outbreak, Treatment, Clinical Research, Vaccine.