European Journal of Biomedical and Pharmaceutical Sciences

CO-RELATION OF HYPERURICEMIA WITH THE SEVERITY OF THE CORONARY ARTERIES OCCLUSION IN INDIAN POPULATION

Sarah Zeeshan*, Swati Baraiya, Sana Faisal, Mihir Ankola, Ravi Shingala, Vatsal Vyas, Ammara Quraishi, Shripal Shah, Nishita Karulkar, Smit Patel

ABSTRACT

Background: Cardiovascular disease is the most common cause of death worldwide. In this study, we tried to find a correlation between serum uric acid levels and the level of severity of coronary arteries occlusion in terms of the number of vessel involvement. Methods: This was a cross-sectional study conducted at a tertiary care hospital associated with medical college. A total of 102 patients were taken in the study. The patients were in the age category of 40-75 years of age. We used standard Automated Analysers for the analysis of blood glucose, lipid profile and serum uric acid level. IBM SPSS (Version 20.0) was used for all the analysis. Results: The patients were divided into 3 groups: single vessel disease (n=40), double vessel disease (n=38) and triple vessel disease (n=24). Biochemical profile of all the groups was obtained by proper lab tests. The group with triple vessel disease had highest amount of LDL cholesterol. This group also had highest number of serum uric acid level. Average was 8.1±3.6 mg/dl. This was followed by double vessel disease followed by single vessel disease. (P value was 0.03). Conclusion: This study proved that with an increase in the serum uric acid level, there is an increase in the level of severity of Coronary Vessel Disease. Also, serum uric acid level is an independent risk factor for coronary artery disease.

Keywords: .