European Journal of Biomedical and Pharmaceutical Sciences

STUDY OF THE PHARMACOLOGICAL PROPERTIES OF THE THREE PLANTS USED IN MEDICINE

Ali BM, Youssouf AG, Djamalladine MD*, Brahim A.A., Zongo C., Sanon S. and Savadogo A.

ABSTRACT

Paveta crassipes, Terminalia avicennioides and Zanthoxylum zanthoxyloides are medicinal plants well-known to traditional therapists from Burkina Faso. The leaves and roots are used in decoction to treat malaria, fever and jaundice. The present study aims to study them properties pharmacological of these three plants used in the Burkinabe traditional medicine. To do this, the method by diffusion in environment agar and the method of dilution in liquid medium have been used to test antimicrobial activities. The antioxidant activity of these extracts was evaluated by the DPPH (1,1-Diphenyl-2-Picrylhydrazyl) method. Extracts methanolic of Terminalia avicennioides and hydromethanolic of Paveta crassipes have exhibited very high (2.17) and high (1.97) antioxidant activity indices, respectively. The results of the antifungal activity showed that extracts of the leaves of Terminalia avicennioides specifically the methanolic and methanol-water extracts, showed greater zones of inhibition (20 mm and 19 mm respectively) for Candida albicans. The hydromethanolic and aqueous extracts of Paveta crassipes exhibit weak antibacterial activity with zones of inhibition (10 mm and 11 mm respectively) for Escherichia coli, higher than those of others extracts. These interesting results justify the use of these plants in the treatment of the diseases infectious.

Keywords: Plants medicinal, Anti-fungal, Antimicrobial, Antioxidant, Burkina Faso.