*Svyatoslav Milovanov, MD, PhD


Enrollment and retention of patients to clinical trial is a barriers to be overcome in order to be succefful in completion of particular clinical trials of any phase. Enrollment and retention is active process and is undergone by many of the factors, influencing oppositedirectly and to managing this factors will allow to follow the main goals of the study. The factors influencing to the enrollmemt of the patients acting during the enrollment period while the factors influencing to the retention begins acting since the first patient enrolled and lasts to the last visit of the last patient. There is a factors which are decreasing the recruitment and last data is reporting up to 80% trials failed due to low or even absence of recruitment on level of sites. Additionally authors have not not defined with the term factors and barriers and this also influence to the action to prevent the fail of study. We will try to highlight as much factors and barriers as we can in order to be known it. Materials and Methods: Review of the publicaitons randomly found on the topic Enrollment and Retention in clinical trials as a barriers and factors influencing to these processes. Study objectives: to highlight Enrollment and Retention in clinical trials as a barriers and factors influencing to these processes. Statistical analysis: there were no statistics and only the observation of journal open sources. Results: It was reviewed the barriers and factors in clinical trials which are influences to the enroolment and retention of patients. First time it was suggested to split the term barriers and factors. Discussion: Recruitment and retention is determining by some authors as a factors and others as a barriers and in meantime the barries and factors could influence to the enrollment and retention. We did listing as much as possible factors and barriers related with retention and recruitment in order to try to find and suggest determination of the terms which will finally lead to success in particular clinical trials.

Keywords: .

[Full Text Article]


Forgot Password  |  Register


Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation


    OCTOBER 2022 Issue has been successfully launched on 1 October 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.


UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS


Copyright From

Covering Letter

                        Author Instruction