Abstract
COMPARISON OF CREATININE PHOSPHO KINASE MYOCARDIAL BAND WITH TROPONIN I FOR MARKING ABILITY OF MYOCARDIUM INFARCTION DISEASE IN SOUTH INDIAN PATIENTS - A PROSPECTIVE COHORT STUDY

Dr. Mohammed Rafiuddin Shoeb*

ABSTRACT

A heart attack, or acute myocardial infarction, is a potentially fatal disorder that develops when the blood supply to the heart muscle is suddenly interrupted, resulting in tissue damage. A blockage in one or more of the coronary arteries frequently causes this. The study group consisted of 40 patients with diagnostic signs of AMI, and 20 healthy age and sex matched controls were enrolled for comparison. It was done to conduct standard investigations like CPK-MB, Troponin-I, and others. According to the study's findings, the diagnosis of acute myocardial infraction requires the use of both CPK-MB and Troponin-I.CPK-MB is up within 10 hours of chest pain and returns to normal levels in almost 2 days, while troponin-I is elevated within 8 hours of chest pain and remains elevated for almost a week. Troponin-I will not be able to indicate the fresh infarction, but Troponin-I is a better indicator of AMI.

Keywords: Acute myocardium infarction; CPK-MB; Troponin I.


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