Abstract
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF NOVEL SERIES OF HYDROXAMIC ACIDS

Taibi Houria, Zerkout Said* and Bekdouche Hafsa

ABSTRACT

This study aims to prepare a novel series of non- cyclic hydroxamic acids which they are Currently occupies a wide fields because of their remarkable biological activities, through the Synthesis of nitrones by the condensation of aldehydes and derivatives of aromatic or aliphatic hydroxylamine as a first step, then these nitrones were oxidized by lead Tetra –acetate (LTA) to give N-acetoxy amide derivatives as a second step, which were hydrated in the acid middle to obtain the approval hydroxamic acids as a last step. Structures of the synthesized compounds were established by elemental analyses, FT-IR, 1HNMR. All the newly synthesized compounds were screened for their antibacterial and antifungal activities. The bioassays indicated that most of the synthesized compounds exhibited moderate to significant antibacterial and antifungal activities.

Keywords: Nitrones , Acetoxy amide derivatives, hydroxamic acids , biological tests, elemental analyses.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: MAY ISSUE PUBLISHED

    MAY 2022 Issue has been successfully launched on 1 May 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT