Ajay Sabale*, Mrunalini Unecha, Prof. Santosh Waghmare, Prof. Andhle A.K. and Dr. Hemant Kamble


Foundation: Osteoporosis is the most well-known constant metabolic bone illness. It has been assessed that in excess of 10 million individuals in the US and 200 million people overall have osteoporosis. Considering that the maturing populace is quickly expanding in numerous nations, osteoporosis could turn into a worldwide test with an effect on the personal satisfaction of the impacted people. Osteoporosis can be characterized as a condition described by low bone density and expanded hazard of fractures because of the disintegration of the bone engineering. A comprehensive multidisciplinary approach to treating osteoporosis includes therapies like calcium and vitamin D, bisphosphonates, oestrogen, selective oestrogen receptor modulators, calcitonin, parathyroid hormone, balance and exercise training programs, and the minimally invasive spine procedures vertebroplasty and kyphoplasty. Here we examine the molecular basis of bone remodeling and the aetiology of osteoporosis, show the pharmacological choices that are currently available, and talk about upcoming therapeutics that target novel mechanisms, investigational medications, and novel prospective therapeutic approaches.

Keywords: .

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