European Journal of Biomedical and Pharmaceutical Sciences

PHYTO-PHARMACOLOGICAL ACTIVITIES AND GC MS STUDIES ON ETHANOLIC LEAF, FLOWER AND SEED EXTRACTS OF LAGERSTROEMIA SPECIOSA (L.) PERS (LYTHRACEAE)

Pavithran S. and Sujatha P.S.*

ABSTRACT

The medicinal activities of Lagerstroemia speciosa plants are generally due to their secondary metabolites. In this research, we summarize the available knowledge of phytochemical and pharmacological activities of L. speciosa. The phytochemical and Gas Chromatography Mass Spectroscopy (GC MS) analysis of ethanolic extracts leaf, flower and seed of L. speciosa revealed that it contained steroids, terpenoids, glycosides, phenolic compounds, α-amino acids, saponins, starch, alkaloids, carbohydrates, organic acids, flavonoids, reducing sugars, tannins and many other active metabolites. L. speciosa (Family: Lythraceae) is native to Asia-tropical and subtropical regions. It has a wide variety of bioactive molecules used as a traditional medicine. The pharmacological properties include antimicrobial, antioxidant, anticancer, antidiabetic, hypolipidemic, antiobesity, anti- inflammatory, analgesic, gastrointestinal, diuretic, thrombolytic, cardiovascular, central nervous, inhibition of TNFα production, xanthine oxidase inhibition, hepatoprotective and nephroprotective effects. The chemical constituent, pharmacological and therapeutic effect of the selected parts of L. speciosa is discussed in this study.

Keywords: Lagerstroemia speciosa, Phyto-constituents, Pharmacology.