European Journal of Biomedical and Pharmaceutical Sciences

EXTRACTION AND ANTIFUNGAL ACTIVITY OF LAWSON AND INDIGO COMPOUNDS

*Pravallika Darru and Dr. S. Sharmila Bhegum

ABSTRACT

Lowsonia inermis commonly known as” HENNA” belongs to the family Litheracae. Henna is widely used as herbal medical all over the world since centuries as an antifungul agent and is sometimes also applied directly to the affected area for dandruff, eczema, scabies, wounds, infectious diseases and helminthiasis and as herbal hair and skin dye. INDIGO dye is distinctively blue in color and it‟s basically an organic compound. It‟s a synthetic dye. Soxhlet and cold percolate extraction methods were investigated for isolation and biological evaluation of bioactive compounds. Obtained results showed that soxhlet extraction at higher temperatures, the yield and recovery decreased due to the degradation of the thermos reactant compounds at several temperature conditions. Antifungul effects of water, methanol extracts of L.inermis leaves and Indigo dye against clinical fungal cultures were investigated and compared with standard antibiotics of Ciprofloxacin and Ampicillin. The fungul isolates were treated with L.inermis methanol extracts were more effective than the water extract using standard method of NCCL, 2000.

Keywords: Lawsonia inermis, Indigofera tinctoria , Extraction , Antifungal activity, Herbal Medicine.