European Journal of Biomedical and Pharmaceutical Sciences

COMPARATIVE STUDY OF MARKETED IBUPROFEN TABLET

Jitendra Gupta, Eshan Pathak, Gazi Md. Talha, Jagdish Kshirsagar, Gaurav Kumar, Dr. Jagdish Chandra Rathi and Devendra Dhariwal*

ABSTRACT

Generic medicine is a pharmaceutical product that can be interchangeable with the innovator medicine. Generic medicine is the same as its corresponding innovator medicine in terms of quality, safety, efficacy, strength, dosage form, route of administration and intended use. However, there are misperceptions that generic medicines are less effective than branded drugs and/or generic drugs are poor quality as compared to brand medicines by health care providers and patients. There are many pharmaceutical companies and distribution channels of drugs worldwide. Unfortunately, circulation of poor quality drug products in the international market increase significantly as a result of ineffective regulation of manufacturing and trading of pharmaceutical products. Therefore, the manufacturing, distribution, storage and use of drugs need to be regulated authorized regulatory institutions. The quality of a pharmaceutical product is essential to ensure the safety of the patients. Different parameters of quality control of pharmaceutical products can guarantee the quality and bioavailability and optimal therapeutic activity. Therefore, the present study was undertaken with the aim of assuring the quality of ibuprofen tablets available in the Indian drug market.

Keywords: Generic medicine, Innovator medicine, Pharmaceutical product, Ibuprofen.