European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF ANXIOLYTIC ACTIVITY OF AQUEOUS EXTRACT OF VIOLA ODORATA ON ANIMAL MODELS

Dr. J. Raghu Ram, Dr. N. Anitha* and Reya Kulsum Nida

ABSTRACT

There are a few universal symptoms of anxiety, and these include irritability, excessive worrying, sweating, restlessness as well as autonomic and neuroendocrine activity. It is possible that predisposing traits (or features) for obsessive anxiety arise from a complicated network of gene-environment intuition during development and life situations. Anxiety may manifest itself in the mind, body, and behavior of animals and humans when a real or perceived threat to health or survival is present. Neuroendocrine, neurotransmitter, and neuroanatomical alterations are common features of mood and anxiety disorders. Among the several neurotransmitters, inhibitory GABA has long been considered the nerve centre for anxiety regulation. When it came to the elevated test, Group 4 (treatment group 2) fared the least. In comparison to the other groups, the group 3 (Treatment group 1) open field test estimate was pivotal. As a bonus, actophotometer results suggested that the protected group encountered much more visit- diminishing situations than the control group.

Keywords: Open field test, Actophotometer, NeuroTransmiter, Anxiety, Neuroendocrine.