European Journal of Biomedical and Pharmaceutical Sciences

IMPACT OF MEDICATION ADHERENCE AND PHARMACEUTICAL CARE ON GLYCEMIC CONTROL IN PATIENTS WITH TYPE II DIABETES MELLITUS

*Shabana Ashraf, Hanna Mariam Sam, Shaziya Shaikh, Arpitha Nair and Dr. Shailesh Yadav

ABSTRACT

This study aimed to determine the impact of medication adherence and pharmaceutical care on glycemic control in patients with type II diabetes mellitus. Retrospective and Prospective observational study was done at mallige hospital among 150 patients for the period of 6 months. (DSMQ) Scale Scoring Tool and Self-reported questionnaire tool used to assess diabetes self management activities associated with glycemic control in common treatment regimens for people with Type 2 Diabetes. Data were analyzed using SPSS software and Anova test was done to check if the means of groups are statistically significant or not. In the study 116 (77.3%) of patients were taking the anti-diabetic drug as advised by the doctor and 34(22.7%) were not taking medicines regularly. The HbA1c test score of 68 patients were found to be excellent in the range of (4- 6%)followed by 52 patients were found to be good(7-8%)and 30 patients found in the range of (9-14)belong to the poor condition. Various Diabetic complications such as diabetic ketoacidosis and hyperosmolar hyperglycemic nonketotic coma observed in non adherent patients. The Cronbach alpha is used to measure the internal consistency, the Cronbach alpha of DSMQ was found to be 0.858, thus reliability statistics of DSMQ found to be better. P value was found to be (p<0.05)which is statistically significant. The correlation of DSMQ and HbA1c was conducted in the study, the correlation R= -0.646 states that as DSMQ score decreases the glycosylated hemoglobin gets higher in value. Overall, patients with good medication adherence have better glycemic control compared with non-adherent ones. This study emphasizes the need for creating more awareness among the general practitioners and clinicians and patients on the importance of medication adherence and pharmaceutical care by conducting more continued medical education programs on drug therapy.

Keywords: Diabetes-self management questionnaire, glycated hemoglobin, Type II diabetes mellitus, Cronbach alpha.