Abstract
ASSESMENT OF REFERENCE VALUES FOR NASAL BONE LENGTH IN FETUSES AT 16-24 WEEKS OF GESTATIONAL AGE IN NORTH-EASTERN INDIAN POPULATION VISITING TERTIARY CARE CENTRE”

*Dr. Shaurya Agarwal and Dr. Nabanita Deka

ABSTRACT

Background: Detection of chromosomal abnormalities were initially based on pregnant women`s age and biochemical markers, however with the advent of sonography, images of fetal nose during 2nd trimester helps in accurately predicting chance of chromosomal birth defect. The objective of this study is to determine reference values for nasal length (NBL) at 16-24 weeks of gestation within North-Eastern Indian population visiting tertiary care Centre. Methods: This descriptive cross-sectional study 400 Pregnant Indian women of North-Eastern region with singleton pregnancies in gestational age of 16-24 weeks in the age group of 18-32 years of age. In this study, Doppler sonography was performed using 1–7 MHz curvilinear array transducers (SAMSUNG RS80A Ultrasound System). Results: Among 400 patients, the fetal nasal bone length was obtained and various relationships between different population based studies were obtained. Conclusion: Our study of 400 patients resulted in linear relationship of fetal nasal bone length to weeks of gestation with subtle differences between various Indian population based studies.However there is a wide variation between Chinese and Japanese populations, suggesting the role of ethnicity.

Keywords: Sonography, fetal nasal bone length, downs syndrome, ethnicity.


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