CORRELATION BETWEEN THYROID NODULE SIZE WITH CYTOLOGICAL CLASSIFICATION AND CANCER IN JORDANIAN PATIENTS
Omar Y. Abu-Zeitoun*, Abdelrazzaq A. Al-Khataleen, Bassam M. M. Aldeikeh, Hatem T. Alhasabeen, Ali M. Alsaweer Lina Al Nahar and Omar Almheerat
ABSTRACT
Background: Confirmation thyroid lobectomy is recommended only based on nodule size. The confirmation of fine needle aspiration to recognize thyroid nodules with cancer is debatable. Objective: To evaluate thyroid nodule size with histopathology as anticipators of cancer risk. Methods: This retrospective investigation recruited 251 patients with thyroid nodules, with average age of 54.86 years (53.51–56.96), of both sexes (83.7% females [210] with 16.3% males [41]) and who had thyroid surgery at King Hussein hospital, King Hussein medical city, Amman, JORDAN, during the period 2016-2019. Before surgery, histopathology according to the British Thyroid Association was obtained containing the size of the dominant nodules. Thy 2(Bethesda II) was labelled negative and Thy 4 - Thy 5 (Bethesda V-VI) were labelled positive for cancer. For a single thyroid nodule, the most prominent cytology was counted and only the dominant thyroid nodule was counted according to the nodular size. Results: 48.2%(121/251) of thyroid nodules were malignant and 130/251 of thyroid nodules were benign (51.8%). The average nodule size was 3.183 cm and 2.311 cm for benign and malignant nodules, respectively. The malignancy for thyroid nodules < 2.5 cm was comparable to those for nodules of 2.5 cm or more (P>0.05). Class (P<0.05) and not nodule size (P>0.05), was correlated with increased malignancy risk. Conclusion: Thyroid nodule size couldn’t precisely anticipate the risk of thyroid cancer. Confirmation thyroid lobectomy alone because of thyroid nodule size of 2.5 cm or more is not recommended.
Keywords: Thyroid nodule size; Cancer; Fine needle aspiration.
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