European Journal of Biomedical and Pharmaceutical Sciences

ESTROUS CYCLE SYNCHRONIZATION AND SUPEROVULATION EFFECT OF LARGININE CEFATOXIME PESSARY (ALCECO®) IN EWES (PART II)

Mohanad A. Al-Bayati*, Hashim Whaib and Ferial Mahdi

ABSTRACT

This study compares superovulation efficiency and estrous cycle synchronization through treatment by L-arginine- Cefatoxime (AlCeco®) 200mg L-arginine per pessary and 500 mg Cefatoxime the estrus cycle-ovulation in ewewas investigating the induced cyclicity of ewe in same time and out of breading season, Estrous cycle synchronization, Superovulation performance, Combined with antibacterial to prevent complication of physiological changes by the following parameters Vaginal smear cytology and type of cells, Total estrous cycle length, Periods of estrous cycle phases, body weight, ovarian weight and ovarian to body weight ratio, Superovulation incidence, total number of follicles and number of sized follicles, total number of atretic follicles with their size, and number of corpora leutea. The results showed obvious estrous cycle synchronization prior superovulation indices as well as efficient at out of breading season. With increase of estrous windows facilitated chance of fertilization as well as hold a protectant effect by reducing bacterial counts. AlCeco®, a one of strategies was counted to synchronize and superovulate in ewe. Adjustments of ovarian functions appearance, as well as the doses and timing of their administration, were made to the protocols based on the ovulation response of the ewe. The project and right pharmaceutic product was sponsored by ministry of higher education and scientific research; research and development department.

Keywords: Ewe, ALCECO, Pessary, L-arginine, Bacteria, Synchronization, Ovary, follicle, Cefatoxime, antibacterial.