European Journal of Biomedical and Pharmaceutical Sciences

A STUDY ON PROPHYLACTIC ADMINISTRATION OF ANTIBIOTICS AND THE RISK OF SURGICAL-SITE INFECTION

Pratap Devi Shankar Sai Prakash*, Nazmeen Tahniyat and Sai Vaishnavi

ABSTRACT

, ABSTRACT Surgical Site Infections were classified according to American Centre for Disease Control (CDC) criteria and identified by active bedside surveillance and post discharge follow up. Antibiotics were selected according to Indian Council Of Medical Research (ICMR), American Society Of Health-System Pharmacists (ASHP), Center For Disease Control And Prevention Guideline for prevention of surgical site infection, 2017, WHO Surgical Site Infection Prevention Guidelines and surgeon’s point of view. The prescribing pattern of antibiotics in general surgery department was studied for a period of one month followed by randomization of patients into two groups. Out of all the 100 surgeries performed in group 1 and group 2, Herniotomy was the major surgery performed in both the groups followed by Lap chole. In group 1, 13 combinations of antibiotics were prescribed, out of which the combination of Cefotaxime and Amoxicillin were majorly prescribed for duration of 7 Days In group 2, 3 antibiotics were prescribed individually, out of which cefotaxime was majorly prescribed (80%) And all the antibiotics were stopped within 24 hours of surgery in group 2. It has been concluded that the timing of administration of antibiotics plays an important role in the prevention of SSI rather than multiple post operative doses. It has been also conclude that the entire team of health care professionals at every step of hierarchy are responsible for taking precautions in the prevention of SSI and everyone should follow the recommendations made by WHO.

Keywords: (SSI)Surgical site infection, Nosocomial Infections Surveillance (NNIS), System.