Abstract
LIQUID BIOPSY FOR CIRCULATING BIOMARKERS IN ORAL CANCER: A REVIEW

Dr. Simran Naresh Verma* and Dr. Deepa Achath Das

ABSTRACT

Oral cancer is one of the most common malignancies worldwide, accounting for 2% of all cases annually and 1.8% of all cancer deaths. Over the past decade, invasive techniques for diagnosing and monitoring oral cancer are slowly being replaced by non- invasive methods such as liquid biopsy. Liquid biopsies from cancer patients have opened up newer avenues in detection and continuous monitoring, treatment based on precision medicine and screening of markers for therapeutic resistance. The purpose of this review is to provide an overview of the current methodologies involved in liquid biopsies and their application in isolating tumour markers for detection, prognosis and monitoring oral cancer treatment outcomes.

Keywords: Liquid biopsy, oral cancer, circulating tumour cells, circulating tumour DNA, exosomes.


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