European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF COMORBID DEPRESSION IN POST-CORONARY ARTERY BYPASS GRAFT SURGERY PATIENTS BY HAMILTON DEPRESSION RATING SCALE (HDRS) AND TREATMENT RESPONSE TO SERTRALINE

*Dr. Neha Garg and Dr. Sanjiv Kale

ABSTRACT

Coronary artery disease (CAD) is one of the leading causes of mortality in developing countries, and it is linked to poor quality of life, disability, and early death. In India, Coronary artery bypass graft surgery (CABG) is the most used surgical treatment for CAD. This technique relies on revascularization, which involves increasing the blood supply to the heart muscle by redirecting blood flow to other arteries. CABG may have a negative impact on the patient’s health, leading to cognitive decline, with depression being the most prevalent symptom. The aim of this study is to screen for presence of depression in patients undergoing CABG by rating the symptoms on the Hamilton Depression Rating Scale (HDRS) before and after initiation of treatment by Sertraline. The goal of this research is to identify early signs of depression after CABG in the Indian setting in order to encourage quick intervention for a better result.

Keywords: coronary artery disease, CABG, depression, HDRS, sertraline.