European Journal of Biomedical and Pharmaceutical Sciences

COMPARATIVE STUDY OF WITHANIA SOMNIFERA L. HERBAL FORMULATIONS BY HPTLC METHOD

Suresh Kumar* and Ramesh Kumar

ABSTRACT

Ashwagandha belong to Solanaceae family has long been used as an Ayurvedic herb against a variety of human diseases. Ashwagandha churna and vatti are an important Ayurvedic formulation containing Withania somnifera L., as one of the prime ingredient of formulation. The combination of drugs and the dosage differ from person to person depending on severity of disease and physiological condition of the body. This research presents a high performance thin layer chromatography based standardization and development of quality of Ashwagandha formulations by using biomarkers compounds. In the process of developing a standardised methodology for quality control of Ayurvedic formulations, the presence of bioactive markers is feasible, and its verification through the HPTLC fingerprint profile is the best technique to distinguish and assess the quality of the finished formulation.

Keywords: Ashwagandha, Churna, HPTLC fingerint, Formulation.