European Journal of Biomedical and Pharmaceutical Sciences

ISOLATION AND CHARACTERIZATION OF THREE NEW COUMARIN DERIVATIVES AND A STEROIDAL GLUCOSIDE FROM THE PLANT OF CUSCUTA REFLEXA

Koushik Saha*, Nahid Sajia Afrin, Md. Awlad Hossain and Md. Farid Uddin

ABSTRACT

Cuscuta reflexa, a parasitic plant, which is commonly known as Swarnalata in Bengali and dodder in English, is an important medicinal plant for its traditional uses and a valuable source of new drugs from Cuscuta genus and Convolvulaceae family. Compounds: 7-hydroxy-6-methoxycoumarin (N-1), 5, 6, 7-trimethoxycoumarin (N-2), 6,7-dimethoxy-5-hydroxycoumarin (N-3) and β-sitosteryl-β-D-glucopyranoside (N-4) were isolated from this plant for the first time. Among these, compounds N-1 was isolated from crude chloroform extract, N-2 & N-3 were isolated from the ethyl acetate soluble part of methanol extract and N-4 was isolated from residual methanol extract. By analyzing various spectroscopic data, the compounds' structures have been elucidated.

Keywords: Cuscuta reflexa, Isolation, Structure elucidation, Spectroscopic methods.