European Journal of Biomedical and Pharmaceutical Sciences

EMBLICA OFFICINALIS (AMLA): A REVIEW FOR ITS PHYTOCHEMISTRY, ETHNOMEDICINAL USES AND MEDICINAL POTENTIALS

Alka Shukla*, Priyanka Pandey, S. Karmakar and Wasim Raja

ABSTRACT

The traditional Indian Ayurvedic medical system's most significant and widely researched plant, Emblica Officinalis (Amla), is discussed along with its preventive efficacies and safety. During an 16-week trial, 14 qualified healthy adult participants were randomly assigned to receive either amla or a placebo (400 mg daily). Vascular function, blood haematology, oxidative and inflammatory indicators, glucose and lipid profiles, urinalysis, and liver hepatotoxicity were the efficacy parameters examined. The main efficacy metric of blood fluidity significantly improved after Amla consumption. Along with a considerable increase in HDL cholesterol and a reduction in LDL cholesterol, benefits were also seen in the secondary endpoints, which included a decrease in von Willebrand factor (vWF), reduced 8-hydroxy-2′-deoxyguanosine (8-OHdG), and thrombin (TM), biomarkers of oxidative stress. After consuming amla, there were no appreciable differences in liver hepatotoxicity, urinalysis, or haematological as compared to baseline or placebo. After consuming amla, no negative side effects, changes in safety parameters, or problems with tolerance were noticed. As a result, Amla supplementation improved endothelial functioning, decreased oxidative stress, and had a tolerable palatability. The present review provided the more information regarding the scientific research and review of Emblica Officinalis (Amla).

Keywords: After consuming amla, no negative side effects, changes in safety parameters, or problems with tolerance were noticed.