European Journal of Biomedical and Pharmaceutical Sciences

GRAPHENE AS CARRIER/NANO CARRIER FOR DRUG DELIVERY SYSTEM

Sarika Sahu*, Gajendra Kumar Sahu, Chumman Lal Sahu, Ritul Pathak, Domendra Yadu and Likeshwar
Verma

ABSTRACT

Graphene, a two-dimensional carbon material, has emerged as a promising candidate for drug delivery systems due to its unique properties. Graphene has a high surface area, excellent mechanical strength, and good biocompatibility, making it an attractive platform for delivering therapeutic agents. In recent years, extensive research has been conducted to explore the use of graphene as a carrier for drug delivery systems for improving the efficacy and specificity of drugs, while reducing their toxicity. Various strategies have been employed to optimize drug loading and release from graphene as a carrier for drug delivery systems. Surface modification, functionalization, and encapsulation are some of the techniques that have been used to enhance the drug delivery efficiency of graphene. These techniques have resulted in increased drug loading capacity, improved release profiles, and enhanced targeting capabilities. graphene as a carrier for drug delivery systems have demonstrated significant potential in preclinical studies. These systems have shown improved pharmacokinetics, bioavailability, and targeted delivery compared to conventional drug delivery systems. Moreover, graphene has the potential to act as a biosensor, allowing for real-time monitoring of drug delivery. Despite its many advantages, the large-scale production, biocompatibility, and safety of graphene as a carrier for drug delivery systems are still major challenges. The biocompatibility of graphene needs to be carefully evaluated to ensure its safety for human use. The high cost of graphene production and the need for reproducible synthesis methods are additional obstacles that must be overcome.

Keywords: Graphene, Drugdelivery, Biocompatibility, Surfacemodification, Functionalization, Encapsulation, Pharmacokinetics, Targeted delivery, Biosensor, Biocompatibility, Safety, Production, Efficacy, Specificity, Carbon material, Two-dimensional, High surfaceare