FOURIER TRANSFORM INFRARED SPECTROSCOPY ANALYSIS OF SIDDHA HERBAL DRUG VASAMBU CHOORANAM
P. Gomathi* and A. Manoharan
ABSTRACT
Background: Siddha Medicine has its own unique way of treating many chronic and challenging diseases.Out of
4448 diseases mentioned in Siddha Literatures, Siddhars have dealt with many life-threatening diseases which
have more prevalence now-a- days.Yugi Muni classified Gunmam into eight types. One among them is
Erigunmam (Peptic Ulcer disease). Vasambu Chooranam is a monoherbal drug indicated for Erigunmam which is
mentioned in the Siddha Literature “Gunapadam MooligaiVaguppu”. Aim: The aim of the study is to assess the
morphology and elemental characterization of Vasambu Chooranam.The functional groups are analysed through
FT-IR spectroscopy and pharmacological roles of functional groups are discussed in the study. Materials and
Methods: The raw drugs are collected, purified and then made into micronized powder. The drug was subjected
into characterization through FT-IR analysis. Results: FTIR Spectroscopic Investigation showed the presence of
characteristic peak values with different useful mixtures of functional groups such as aromatic compounds,
sulfoxide, secondary alcohol and carboxylic acid which is responsible for its functional activity. Conclusion: The
instrumental analysis FT-IRS study of Vasambu Chooranam revealed the presence of functional groups through
the stretch and bends which is responsible for its functional activity. The functional groups in Vasambu
Chooranam possess analgesic and anti-inflammatory activities. This will ensure the efficacy and therapeutic effect
of the drug.
Keywords: Fourier Transform Infrared Spectroscopy, Vasambu, Peptic Ulcer, Siddha Medicine, Acorus calamus.
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