European Journal of Biomedical and Pharmaceutical Sciences

EFFECTS OF DIABETES MELLITUS IN PULMONARY TUBERCULOSIS

Radhika Jaiswal, Abhishek Vadher*, Rajkumar Doshi, Yash Shah, Rahul Chauhan, Vaibhav Patel and Priyanka Kugamoorthy

ABSTRACT

We studied the effects of Diabetes on Tuberculosis. For this, we had taken 50 patients with Tuberculosis and Diabetes both and 50 controls who had only Diabetes but no TB infection. The cases and the controls were divided into 2 categories: Controlled and uncontrolled diabetes. For this the cut off used was HbA1c of 7%. Chest X rays were also taken from the TB patients and it was compared with other studies. The study showed that Tuberculosis is more common in uncontrolled Diabetic patients as compared to patients with controlled Diabetes. The p value is <0.01 which suggests the statistically significant result. Other interesting findings is that in tuberculosis patients having uncontrolled diabetes, bilateral lobe involvement is more common. This is due to the decrease in the immunity in diabetes. The most common involvement on chest x ray was consolidation followed by cavity followed by nodule.

Keywords: Diabetes Mellitus, Tuberculosis, Infection.