European Journal of Biomedical and Pharmaceutical Sciences

BULLOUS PEMPHIGOID IS THE MOST COMMON AUTOIMMUNE SUBEPIDERMAL BLISTERING DISEASE IN GERIATRIC PERSONS

Prof. Dr. Dhrubo Jyoti Sen*

ABSTRACT

Pemphigus is a disease that causes blistering of the skin and the inside of the mouth, nose, throat, eyes, and genitals. The disease is rare in the United States. Pemphigus is an autoimmune disease in which the immune system mistakenly attacks cells in the top layer of the skin (epidermis) and the mucous membranes. Pemphigus vulgaris is caused by a problem with the immune system, which is the body's defense against infection. Instead of attacking germs, something goes wrong with the immune system and it attacks the skin by mistake. This damages the skin and causes blisters to appear. Bullous pemphigoid is a rare skin condition that mainly affects older people. It usually starts with an itchy, raised rash. As the condition develops, large blisters can form on the skin. It may last a few years and sometimes causes serious problems, but treatment can help manage the condition in most cases.

Keywords: Skin, Epidermis, Dermis, Itching, Pemphigus, Bullous, ELISA.