European Journal of Biomedical and Pharmaceutical Sciences

EFFECT OF ARDISEA SOLANACEA BARK ON ANTHELMINTIC ACTIVITY

*Krishnapriya P.G. and Dr. Lal Prasanth M.L.

ABSTRACT

This study was aimed to investigate the anthelmintic activity of Ardisia Solanacea bark, using Indian earthworm Pheretima posthuman. Tribals are traditionally used Ardisia solanacea plant for different disease. The hydroalcoholic extraction of ardisia solanacea was subjected to preliminary phytochemical screening to find out the major phytoconstituents present in the extraction. Various concentration of extraction (50 mg/dl and 100 mg/dl) were tested which involved determination of paralysis time and death time of the worm. Albendazole (100 mg/ml) was used as standard. Preliminary phytochemical test showed that the extraction contains various phytoconstituents such as alkaloids, tannins, flavonoids, saponins,carbohydrates. The result of the study reveals the dose dependent anthelmintic activity of hydroalcoholic extract of Ardisia solanacea bark. Further investigation is needed to find out the specific constituent which is responsible for anthelmintic activity.

Keywords: Ardisia solanacea, pheretima posthuma, phytoconstituents, anthelmintic activity, Albendazole, hydroalcoholic extract.