European Journal of Biomedical and Pharmaceutical Sciences

EFFECT OF APIGENIN, RUTIN AND TARAXEROL (BIOLOGICALLY ACTIVE COMPOUNDS) ON DEVELOPMENT OF FILARIAL VECTOR CULEX QUINQUEFASCIATUS

Abhay Deep Johnson*, Vikas Chandra Verma and Ajay Singh

ABSTRACT

Plant based formulations and extracts can be used in environmental products which has proved to be a potential insecticide. Developmental investigations of biologically active compounds i.e. Apigenin from the leaves of Jatropha gossypifolia (Figure 1,2) Rutin and Taraxerol are extracted from the leaves of Codiaeum variegatum (Figure 3,4,5) against larvae of Culex quinquefasciatus was studied . The active compounds i.e. Apigenin, Rutin and Taraxerol extracted through ethyl alcohol, acetone and petrol solvents respectively from the leaves of Euphorbious plants was administered from lower dose (9.31 mg/L) to higher dose (13.81 mg/L) of Apigenin, lower dose (7.55 mg/L) to higher dose (10.55 mg/L) of Rutin and lower dose (7.30 mg/L) to higher dose (12.10 mg/L) of Taraxerol respectively which significantly resulted in the reduction of adult emergence, larval survival and pupation in the treated groups of first instar larvae of Culex quinquefasciatus larvae. It can be used as an ecofriendly method to manage the population of filarial vector Culex quinquefasciatus.

Keywords: Codiaeum variegatum, Jatropha gossypifolia, Apigenin, Rutin, Taraxerol and Culex quinquefasciatus.