European Journal of Biomedical and Pharmaceutical Sciences

REPELLENT ACTIVITIES OF ETHANOLIC EXTRACT OF HYPTIS SUAVEOLENS LINN. (LAMIACEAE) AND AZADIRACHTA INDICA (MELIACEAE) LEAVES IN MALARIA VECTOR CONTROL IN DOGBO DISTRICT IN SOUTH-WESTERN BENIN, WEST AFRICA

Nazaire Aïzoun* and Arlette Adjatin

ABSTRACT

Background: The use of chemical insecticides causes important damages to environment and human health and there is a need to search for alternative solutions. Objective: The current study was aimed to evaluate the repellent activities of ethanolic extract of Hyptis suaveolens Linn. (Lamiaceae) and Azadirachta indica (Meliaceae) leaves on Anopheles gambiae s.l female adult mosquitoes in malaria vector control in Dogbo district in south-western Republic of Benin. Methodology: Larvae of Anopheles gambiae s.l mosquitoes were collected from breeding sites using the dipping method in June 2022 during the great rainy season in Dogbo district. Repellent activities of ethanolic extracts of both tree leaves were measured with different concentrations of 1mg/cm2, 2mg/cm2, 3mg/cm2, 4mg/cm2 and 5mg/cm2. Results: The results showed that the leaves of both trees have repellent effects on Anopheles gambiae sensu lato female adult mosquitoes. Conclusion: Both ethanolic extracts of Hyptis suaveolens Linn. and Azadirachta indica leaves are found to be effective in the repellency against the bites of Anopheles gambiae sensu lato female adult mosquitoes.

Keywords: Hyptis suaveolens Linn, Azadirachta indica, malaria control, Benin.