European Journal of Biomedical and Pharmaceutical Sciences

A PROSPECTIVE OBSERVATIONAL STUDY ON CLINICAL MANIFESTATIONS OF POLYCYSTIC OVARIAN DISEASE IN YOUNG ADULTS

Sreenu Thalla*, Pasupuleti Vyshnavi, Potluri Srilakshmi, Shaik Khanes Fathima, Motupalli Sri Maha Lakshmi, Melam Sri Varshitha and Rama Rao Nadendla

ABSTRACT

Polycystic Ovarian Disease (PCOD), also known as Polycystic Ovary Syndrome (PCOS), is a prevalent endocrine disorder affecting reproductive-aged women worldwide. This prospective observational study aims to investigate the clinical manifestations of PCOD in young adults, providing valuable insights into the diverse symptomatic presentations and potential risk factors associated with the condition. Clinical data, hormonal profiles, ultrasonographic evaluations of the ovaries, and metabolic parameters were also recorded. The study revealed menstrual irregularities as the most common clinical manifestation, with irregular menstrual cycles, amenorrhea, and oligomenorrhea prevalent in the cohort. Hyperandrogenism, indicated by hirsutism, acne, and alopecia, was also frequently observed. Transvaginal ultrasound assessments confirmed polycystic ovarian morphology, with multiple cysts and increased ovarian volume present in a significant proportion of participants. The findings underscore the importance of early detection, personalized treatment plans, and comprehensive patient care that includes mental health support alongside medical management. By addressing the diverse symptomatic presentations and potential risk factors associated with PCOD, healthcare professionals can optimize management strategies and improve the overall quality of life for young adults living with this complex endocrine disorder. Further research should explore long-term treatment outcomes and consider addressing potential limitations to enhance the study's validity and generalizability.

Keywords: Polycystic Ovary Syndrome, Hyperandrogenism, Insulin resistance, Metabolic disturbances.