European Journal of Biomedical and Pharmaceutical Sciences

STANDARDIZATION AND COMPARATIVE PHARMACEUTICAL STUDY OF SHUNTHI KSHEERPAKA POWDER PREPARED FROM TWO DIFFERENT TYPES OF MILK MEDIA W.S.R. TO ITS SPRAY DRYING METHOD

Shreenadevi L. Patel*, Upendra U. Zala and Meenu Bharti Sharma

ABSTRACT

Ayurveda is the ancient science of life in which pharmaceutical preparations are the basic and mandatory part. In Bhaishajya Kalpana Vigyana, Panchavidha Kashaya Kalpanas are the basic Kalpanas for all other Upkalpanas.[1] Ksheerpaka Kalpana is one of the important and differerent dosage form and also Upkalpana of Kvath Kalpana. This unique preparation mentioned in well-known ayurvedic classics like Charak samhita, Sushrut Samhita,Astang Sangarah, Astang Hridayam, Kasyapa Samhita, vrindmadhav, Chakradutta, Vangasena, Bhavprakash, Yogaratnakara, BhaishajyaRatnavali, Gadanigraha, Brihat Nighantu Ratnakara and Sharandhara Samhita. Ksheerpaka Kalpana is a formulation in which Ksheera is the main media of administration.It has a property of water soluble, lipid soluble and protein soluble constituents.For making milk digestable and Laghupaki Shunthi Ksheerpaka is commonly used by practitioners.[2] It is also used in Amavata,Ajirna,Udaavarta,Chardi, Hikka, Aadhmana,Shula and Kasa.[3] we usually used Godugdha for making Ksheerpaka. While in Chakradutta Samhita Aacharya Chakradutta[5] mentioned Shunthi Siddha Aja Ksheer (Goat milk) for treatment of Hikka.So here is an attempt to make a Shunthi Ksheerpaka based on Aacharya Sharangadhara’s Ksheerpaka proportion (1:8:32) by using two different milk media (Godugdha & Ajadugdha). Ksheerpaka is very difficult to prepare outdoor and due to very low shelf life (Sadyosevana) it’s impossible to carry.So we will convert Shunthi Ksheerpaka in a powder form through spray dried method and evaluate efficacy and compare both types of spray dried powder.Thus we will give an insight for such instant preparation in to stable modified dosage form.

Keywords: Ksheerpaka, Spray drying, Shunthi, Go-dugdha, Aja-dugdha.