*Rohit Gurnani, Divyanshi Prakash and Dr. Sunil K. Batra


Significant advancements have been made in the field of drug delivery systems, addressing physiological challenges such as short gastric residence periods and unpredictable gastric emptying times. Gastro-retentive Dosage Forms (GRDF) refer to dosage forms designed to remain in the stomach for an extended period. Various methods have been employed to prolong gastric residence time, including floating drug delivery systems, swelling and expanding systems, polymeric bio-adhesive systems, high-density systems and delayed gastric emptying systems. The realm of medication-based disease treatment is entering a new era, with a growing range of innovative drug delivery technologies becoming available for clinical use. Floating Drug Delivery Systems (FDDS) is a gastro-retentive dosage form utilized to achieve prolonged gastric residency time. This review aims to compile recent literature on floating drug delivery systems, focusing particularly on the main mechanisms employed to achieve gastric retention. Sustained oral release of gastrointestinal dosage forms offers numerous advantages for drugs absorbed in the upper sections of the gastrointestinal tract and those with local gastric action. The review covers the physiology of gastric retention, factors influencing gastric retention time, excipient variables that impact gastric retention, approaches to designing single-unit and hydrodynamically balanced systems, multi-unit floating structures, as well as detailed discussions on their classification, formulation, evaluation, and a few applications of these systems.

Keywords: Gastro retentive dosage forms, Floating drug delivery systems.

[Full Text Article]


Forgot Password  |  Register


Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation


    DECEMBER 2023 Issue has been successfully launched on 1 DECEMBER 2023.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.


UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS


Copyright From

Covering Letter

                        Author Instruction