European Journal of Biomedical and Pharmaceutical Sciences

A REVIEW ON CINNAMON BARK FORMULATION AND EVALUATION HAVING A WOUND HEALING PROPERTIES

Samuvel Raj A., Gopi S., Ragul G., Hardha B.* and Senthil Kumar M.*

ABSTRACT

By using capillary GC and GCIMS, the cinnamon bark, leaf, root, and fruit were examined for their essential oils. Six and y-cadinene (36.0%), cadinol (7.7%), and 8-caryophyllene (5.6%) were the main components of cinnamon fruit oil. About Sesquiterpenes made up 84% of the cinnamon fruit oil, but other cinnamon elements did not. included fewer than 9% of the chemicals in this category. The phenyl propanoids main components of cinnamon bark, leaf, and root oils, whereas monoterpenes were found in root oil as the predominant components (95%). Powdered Cinnamomum zeylanicum (cinnamon bark) was treated with subcritical water in a semi-continuous system at 150 and 200°C with a constant flow rate of 3 mL/min and pressure of 6 MPa. Major flavouring substances such cinnamaldehyde, cinnamic acid, cinnamyl alcohol, and coumarin were recovered with lower recoveries than when methanol was used, indicating that these substances may have degraded during the subcritical water treatment. The subcritical water treatment produced the acids vanillic, caffeic, ferulic, p-coumaric, and protocatechuic. In terms of the quantity of components and recovery, subcritical water extraction was superior to methanol (50% v/v) extraction to produce these acids, especially at 200°C. In comparison to methanol extraction, subcritical water treatment at 200°C produced a greater total phenolic content and DPPH radical scavenging activity.

Keywords: cinnamaldehyde, cinnamic acid, cinnamyl alcohol, and coumarin.