European Journal of Biomedical and Pharmaceutical Sciences

STUDY OF PHYTOCHEMICALS AND ANTIEPILEPITIC ACTIVITY OF HYDROALCOHOLIC EXTRACT OF PUERARIA TUBEROSA

*Roshnee Ghorse, Rahim Khan, Dr. Ravi Prakash, Dr. Brajesh Ku. Arjariya and Sheenam Mansuri

ABSTRACT

Epilepsy remains a challenging neurological condition affecting millions worldwide, necessitating innovative therapeutic approaches. Phytochemicals, bioactive compounds abundant in various plants, have drawn attention for their potential to address epilepsy. Pueraria tuberosa, known as "Indian Kudzu" or "Vidari Kanda," is a plant rich in phytochemicals, offering a promising avenue for research into its antiepileptic properties. This study delves into the phytochemical composition of the hydroalcoholic extract of Pueraria tuberosa, aiming to identify and quantify specific bioactive compounds, including flavonoids, alkaloids, saponins, and polyphenols. Furthermore, it rigorously evaluates the extract's antiepileptic activity through comprehensive in vitro and in vivo experiments. These assessments encompass seizure models, neurotransmitter level measurements, and oxidative stress marker evaluations. Understanding the phytochemical constituents of the Pueraria tuberosa extract and their potential effects on epileptic seizures holds significant therapeutic potential. This research contributes to the expanding knowledge base of natural remedies for epilepsy, offering new avenues for improving the quality of life for those affected by this challenging condition. Additionally, it aligns with the broader goal of identifying safe and effective alternatives to conventional antiepileptic drugs, addressing the unmet needs in epilepsy management.

Keywords: antiepilepitic activity, hydroalcoholic, Pueraria Tuberosa, herbal.